Recently, a team of researchers Li Bei from Changchun Institute of Optics and Mechanics, Chinese Academy of Sciences, and Professor Wang Wei from Peking University collaborated to apply the core product of HOOKE PRECI SCS single cell sorting instrument. The article titled "PICKING SINGLE CELLS from 10 ML SAMPLE BASED ON A MICROFILTRATION - LIFT COMBINATION PLATFORM" was published on MEMS, aiming to separate single cells from 10 mL samples based on the microfiltration LIFT combination platform.

Abstract

This paper reported a microfiltration-laser induced forward transfer (microfiltration-LIFT) combination platform that fulfilled an automatic single-cell picking-up capability from a large volume sample (more than 10 mL). Cells were first rapidly enriched by a gravity-driven microfiltration based on previously-reported PERFECT filters, and the captured-cells on the filter could then be accurately picked up at single-cell resolution by the LIFT system using a focused laser with a spot size of ~10 μm. This platform is a promising method to pick up single cells from large volume sample for subsequent heterogeneity molecular analyses.

The paper links：

https://ieeexplore.ieee.org/document/10052221